Epertinib

View Clinical trials for Epertinib Get Epertinib Patent Info for Free

S-222611 inhibits the growth of NCI-N87 tumor and phosphorylation of epidermal growth factor receptor (EGFR) and human epidermal growth factor 2 (HER2) in the tumor

Inn NameEpertinib
Lab CodesS-222611
Chemical NameN-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-[(1Z)-N-{[(3R)-morpholin-3-yl]methoxy}but-2-ynimidoyl]quinazolin-4-amine
Chemical StructureEpertinib.png
Molecular FormulaC30H27ClFN5O3
SmilesCC#C\C(=N/OC[C@H]1COCCN1)C1=CC=C2N=CN=C(NC3=CC(Cl)=C(OCC4=CC(F)=CC=C4)C=C3)C2=C1
Cas Registry Number908305-13-5
New Molecular EntityYes
OriginatorShionogi
Mechanism Of ActionEpidermal growth factor inhibitor, ERBB 2 receptor antagonist
Who Atc CodesL01 (Antineoplastic Agents)
Ephmra CodesL1 (Antineoplastics)

Free counters!