Evobrutinib

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Evobrutinib is a highly selective inhibitor of the Bruton’s tyrosine kinase (BTK), which is important in the ­development and functioning of various immune cells including B ­lymphocytes and macrophages. Preclinical research suggests it may be therapeutically useful in certain autoimmune diseases.

Inn NameEvobrutinib
Lab CodesM-2951, MSC-2364447C
Chemical StructureEvobrutinib.png
SmilesNC1=NC=NC(NCC2CCN(CC2)C(=O)C=C)=C1C1=CC=C(OC2=CC=CC=C2)C=C1
Cas Registry Number1415823-73-2
New Molecular EntityYes
OriginatorMerck Serono
Mechanism Of ActionBruton's tyrosine kinase (Btk) inhibitor
Who Atc CodesM01 (Antiinflammatory and Antirheumatic Products)
Ephmra CodesM1 (Anti-Inflammatory and Anti-Rheumatic Products)
Indication Systemic lupus erythematosus (SLE)

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