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PF-02545920 is a PDE10 Inhibitor that is in development at Pfizer for Huntington’s Disease and as an adjunctive treatment for Schizophrenia

Inn NameMardepodect
Usan NameMardepodect
Lab CodesPF-02545920, PF-0254920, PF-2545920, MP-10
Chemical Name2-({4-[1-methyl-4-(pyridin-4-yl)-1H-pyrazol-3-yl]phenoxy}methyl)quinoline
Chemical StructureMardepodect.png
Molecular FormulaC25H20N4O
Cas Registry Number898562-94-2
Orphan Drug StatusYes
Orphan IndicationHuntington's disease
New Molecular EntityYes
Mechanism Of ActionPhosphodiesterase-10 (PDE-10) inhibitor
Who Atc CodesN05A (Antipsychotics)
N07X (Other Nervous System Drugs)
Ephmra CodesN5A (Antipsychotics)
N7X (All other CNS drugs)
IndicationSchizophrenia, Huntington's Disease

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